Born on 18 October 1918, at Chaniá, Crete, Mitsotakis served as prime minister of Greece from 1990 to 1993. With origins from a political family, as his father and grandfathers were members of the Greek parliament, and his uncle was Eleutherios Venizelos, a politician that has served too as former prime minister.
Mitsotakis studied law and economics in Athens and was first elected to the Greek parliament in 1946 as a member of the Liberal Party. In the early 1960s he joined the new Centre Union, a centre-left coalition organized by Georgios Papandreou. In July 1965, Mitsotakis, with other Centre Union members of parliament, defected from the party and joined the pro-monarchist force, supporting King Constantine II.
During the Greek military junta of 1967-1974, Mitsotakis fled to Paris, France and returned in 1973. Mitsotakis re-entered parliament in 1977 and in 1978 after founding centrist New Liberal Party, he accepted a cabinet post in the government of Konstantinos Karamanlis, before joining right-wing New Democracy Party.
It was 1984 when Mitsotakis became New Democracy’s party leader, and in 1990 he became prime minister after defeating George Papandreou’s son Andreas Papandreou PASOK Social Democrat Party. In 1993 New Democracy lost its majority in parliament and Mitsotakis resigned as leader of New Democracy.
His son Kyriakos Mitsotakis was elected on 10 January 2016, president of the New Democracy. His sister Dora Bakogianni is currently a parliament member for New Democracy.